Background: We aimed to evaluate a modified endotracheal tube containing upper and lower balloons for\nanesthetic administration among patients undergoing laparoscopic cholecystectomy.\nMethods: Ninety patients scheduled to undergo laparoscopic cholecystectomy were randomly allocated to 3 equal\ngroups: group A (conventional tracheal intubation without endotracheal anesthesia); B (conventional tracheal\nintubation with endotracheal anesthesia); and C (tracheal intubation using a modified catheter under study). Blood\npressure, heart rate, angiotensin II level, blood glucose level, airway pressure before anesthesia (T1) were measured\nimmediately after intubation (T2), 5 min after intubation (T3), and immediately after extubation (T4). The postextubation\npain experienced was evaluated using the Wong-Baker Face Pain scale. Adverse reactions within 30 min\nafter extubation were recorded.\nResults: Systolic blood pressure, diastolic blood pressure, angiotensin II, and blood sugar level in group C at T2, T3\nand T4, and heart rate at T2 and T4 were significantly lower than those in group A (P < 0.05); systolic blood pressure\nand blood sugar at T4, and angiotensin II levels at T2, T3, and T4 were significantly lower than those in group B\n(P < 0.05). Patients in group C reported the lowest post-extubation pain (P < 0.05 vs. Group A), and the lowest\nincidence of adverse events such as nausea, vomiting, and sore throat than that in groups A and B (P < 0.05).\nConclusion: The modified endotracheal anesthesia tube under study is effective in reducing cardiovascular and\ntracheal stress response, and increasing patient comfort, without inducing an increase in airway resistance.
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